----- 海外信息　 记录号 = 3989 ------

题目: 1999年全球最畅销的近150个处方药(之二)(2000.12.18)

　　 根据《Med.Ad.News》报道，现将1999年全球最畅销处方药中的近150个药物
及其相关情况编译、整理如下：
'排序(年)'商品名/一般名'生产公司'适应症'销售额(百万美元)'年增长率(%)'
'1999'1998'
'51'88'Combivir/拉米夫定+齐多夫定(lamivudine+zidovudine)'Glaxo Wellc-
ome'艾滋病感染'736.0'66.3'
'52'43'Lupron/亮丙瑞林(leuprorelin)'TAP Holdings'前列腺癌'730.0'-3.3'
'52'49'Pulmicort/布地奈德(budesonide)'AstraZeneca'哮喘'730.0'5.6'
'54'68'Accutane/异维A酸(isotretinoin)'Hoffmann-La Roche'痤疮'705.9'
24.9'
'55'57'Lamisil/特比萘芬(terbinafine)'Novartis'脚癣'700.7'12.0'
'56'63'Zoladex/戈舍瑞林(goserelin)'AstraZeneca'子宫内膜异位、前列腺癌'
686.0'9.6'
'57'51'Ceftin/头孢呋辛酯(cefuroxime)'Glaxo Wellcome'细菌感染'680.0'-0.2'
'58'60'Zofran/恩丹西酮(ondansetron)'Glaxo Wellcome'恶心和呕吐'674.0'4.5'
'59'53'Zovirax/阿昔洛韦(aciclovir)'Glaxo Wellcome'带状疱疹、生殖器疱疹
和水痘'667.0'-0.1'
'60'52'Crixivan/英地那韦(indinavir)'Merck'艾滋病感染'665.0'-1.5'
'61'46'Intron A/α2b-干扰素(interferon alpha-2b)'Schering-Plough'毛细
胞性白血病、卡拨济氏肉瘤、丙型肝炎'650.0'5.0'
'62'69'Zerit/司他夫定(stavudine)'Bristol-Myers Squibb'艾滋病感染'635.0'
15.2'
'63'106'Avonex/β1a-干扰素(interferon beta-1a)'Biogen'多发性硬化病'
621.0'57.3'
'64'56'Diprivan/双异丙酚(disoprofol)'AstraZeneca'麻醉'608.0'-6.9'
'65'70'Buspar/丁螺环酮(buspirone)'Bristol-Myers Squibb'焦虑症'605.0'
13.9'
'66'45'Mevacor/洛伐他汀(lovastatin)'Merck'高血脂症'600.0'-19.5'
'66'73'Paraplatin/卡波铂(carboplatin)'Bristol-Myers Squibb'卵巢癌'
600.0'14.3'
'66'44'Rezulin/曲格列酮(troglitazone)'Warner-Lambert,三共'Ⅱ型糖尿病'
600.0'-19.8'
'69'62'Ventolin/沙丁胺醇(albuterol)'Glaxo Wellcome'支气管扩张'596.0'
-5.4'
'70'108'Aredia/帕米磷酸钠(disodium pamidronate)'Novartis'高血钙症、骨
Paget氏病'588.0'55.6'
'71'71'Viracept/奈非那韦(nelfinavir)'Warner-Lambert'艾滋病感染'585.0'
10.8'
'72'58'Hytrin/特拉唑嗪(terazosin)'Abbott'前列腺增生，高血压'580.0'
-10.8'
'73'73'Primaxin/亚胺培南+西司他丁(imipenem+cilastatin)'Merck'细菌感染'
575.0'9.5'
'74'75'Nolvadex/他莫昔芬(tamoxifen)'AstraZeneca'乳腺癌'573.0'8.9'
'75'79'Wellbutrin/安非他酮(bupropion)'Glaxo Wellcome'抑郁症'572.0'12.4'
'76'96'Zyrtec/西替利嗪(cetirizine)'Pfizer'过敏反应'552.0'32.7'
'77'257'Plavix/氯吡格雷(clopidogrel)'Bristol-Myers Squibb,Sanofi'心肌
梗塞'547.0'279.9'
'78'35'Engerix-B/乙型肝炎疫苗'SmithKline Beecham'乙型肝炎'540.0'2.1'
'79'85'Flonase/氟替卡松'Glaxo Wellcome'过敏性鼻炎'539.0'18.6'
'80'76'Versed/咪达唑仑(midazolam)'Hoffmann-La Roche'麻醉'536.4'7.6'
'81'82'Coumadin/华法林(warfarin)'DuPont'深度静脉栓塞'535.0'-2.7'
'82'87'Toprol-XL/美托洛尔(metoprolol)'AstraZeneca'高血压'531.0'18.0'
'83'-'Rebetron/α2b-干扰素+利巴韦林(ribavirin)'Schering-Plough'丙型肝炎'
530.0'430.0'
'84'65'Epivir/拉米夫定'Glaxo Wellcome'艾滋病感染'527.0'-11.4'
'85'40'Cardizem/地尔硫卓(diltiazem)'Aventis'心绞痛'522.0'29.9'
'86'47'Procardia XL/硝苯地平'Pfizer'高血压，心绞痛'521.0'-27.0'
'87'67'Sporanox/伊曲康唑(itraconazole)'Johnson & Johnson'真菌感染'
515.0'-0.8'
'88'109'Taxotere/多烯紫衫(docetaxel)'Novartis'乳腺癌'514.5'46.2'
'89'86'Accupril/喹那普利(quinapril)'Warner-Lambert'高血压，充血性心力
衰竭'514.0'13.2'
'90'91'Nizoral/酮康唑(ketoconazole)'Janssen'真菌感染'510.0'6.3'
'91'81'Tenoretic,Tenormin/阿替洛尔及其+氯噻酮(atenolol及其+chlorthal-
idone)'AstraZeneca'高血压'509.0'1.4'
'92'120'Xalatan/拉坦前列素(latanoprost)'Pharmacia'高眼压'507.3'52.8'
'93'61'Capoten/卡托普利(captopril)'Bristol-Myers Squibb'高血压'500.0'
-21.4'
'93'98'Ceredase,Cerezyme/阿糖苷酶，伊糖苷酶(alglucerase,imiglucerase)'
Genzyme'脑苷酯沉积症'500.0'21.7'
'93'198'Singulair/蒙特司特(montelukast)'Merck'哮喘'500.0'157.7'
'96'486'Xenical/奥立司他(orlistat)'Hoffmann-La Roche'肥胖症'499.2'500.8'
'97'135'Divoan/缬沙坦(valsartan)'Novartis'高血压'493.3'80.9'
'98'99'Betaseron/β1b-干扰素(interferon beta-1b)'Schering AG'多发性硬
化病'483.6'18.2'
'99'-'Vioxx/罗非考西(rofecoxib)'Merck'骨关节炎及其疼痛'472.0'-'
'100'152'Harnal/坦索罗辛(tamsulosin)'山之内'前列腺增生'465.4'32.6'
(F)